Bin Wang, PhD
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see his profile.
Dr. Wang's Laboratory is investigating the roles of parathyroid hormone (PTH)/PTH related protein (PTHrP)–activated PTH receptor in musculoskeletal diseases.
- Characterization of bimodal effects of PTH on bone metabolism. The long-term objective is to identify new compounds that can enhance the anabolic effect of PTH or PTHrP for the treatment of osteoporosis.
- Determining whether and how PTHrP plays a pathogenic role in articular cartilage degeneration (osteoarthritis) during aging.
- Characterization of the interaction of PTH receptor with other GPCRs. The purpose of this research will illustrate how PTH receptor coordinates with other GPCRs to maintain musculoskeletal homeostasis.
The overall mission of Dr. Wang’s research is to advance knowledge in the fields of GPCR biological and musculoskeletal disease research and translate the scientific discoveries into improved health.