Philadelphia University + Thomas Jefferson University
Sidney Kimmel Medical College
Department of Medicine

Whellan, David

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David J. Whellan, MD, MHS, FACC, FAHA

Contact Dr. Whellan

1015 Chestnut Street
Suite 317
Philadelphia, PA 19107

(215) 955-2636
(215) 503-7420 fax

Medical School

MD, Washington University School of Medicine
Master Health Science in Clinical Research, Duke University


Hospital of University of Pennsylvania (HUP)


Clinical Cardiology, Duke University Medical Center

Board Certification

Internal Medicine
Cardiovascular Disease

Hospital Appointment

Thomas Jefferson University Hospital

Expertise & Research Interests

Dr. Whellan is the Principal Investigator of Jefferson Regional Clinical Center for the NIH HF Network, one of 9 centers across the United States selected to participate in a series of novel heart failure clinical trials. In addition, he serves as the Associate Provost for Clinical Research at Thomas Jefferson University and Associate Dean for Clinical Research at Sidney Kimmel Medical College.

He has authored over 175 peer-reviewed articles, reviews, abstracts, and book chapters on cardiomyopathy; and is an associate editor for the Journal of the American College of Cardiology Heart Failure journal.


Most Recent Peer-Reviewed Publications

  1. The Impact of a Transition of Care Program on Acute Myocardial Infarction Readmission Rates
  2. Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial
  3. Change Is Not Always Good
  4. Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study
  5. Efficacy and safety of spironolactone in acute heart failure: The ATHENA-HF randomized clinical trial
  6. Effect of natriuretic peptide–guided therapy on hospitalization or cardiovascular mortality in high-risk patients with heart failure and reduced ejection fraction: A randomized clinical trial
  7. Effect of oral iron repletion on exercise capacity in patients with heart failure with reduced ejection fraction and iron deficiency the IRONOUT HF randomized clinical trial
  8. A Novel Rehabilitation Intervention for Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Pilot Study
  9. Exercise Training in Patients With Chronic Heart Failure and Atrial Fibrillation
  10. Cognitive Outcomes After Coronary Artery Bypass Grafting
  11. Aerobic exercise training and general health status in ambulatory heart failure patients with a reduced ejection fraction—Findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)trial
  12. Cardiovascular Outcomes With Minute Ventilation–Targeted Adaptive Servo-Ventilation Therapy in Heart Failure: The CAT-HF Trial
  13. Easy to Predict, Difficult to Prevent
  14. Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale
  15. Does the Implantable Cardioverter-Defibrillator Benefit Vary With the Estimated Proportional Risk of Sudden Death in Heart Failure Patients?
  16. Inpatient management of heart failure: Are we shooting at the right target?
  17. Sleep overnight monitoring for apnea in patients hospitalized with heart failure (SOMA-HF study)
  18. Socioeconomic and partner status in chronic heart failure: Relationship to exercise capacity, quality of life, and clinical outcomes
  19. Multinational and multiethnic variations in health-related quality of life in patients with chronic heart failure
  20. Impact of the 2013 American College of Cardiology/American Heart Association cholesterol guidelines on the prescription of high-intensity statins in patients hospitalized for acute coronary syndrome or stroke