Philadelphia University + Thomas Jefferson University

Proposal Instructions

Goal: To fund transformational science initiatives from Jefferson faculty members, and to generate data in support of new or longstanding areas of basic and clinical/translational research; this grant mechanism is open to imulti-investigator proposals and proposals from individual investigators.

Cover Page Information and Abstract

All basic information including name(s) of investigator(s), department, contact and other information requested on the InfoReady Portal should be provided as requested for all investigators.


An abstract/summary of the proposal must be included at the site provided on the InfoReady Portal

Justification-half page

This section should be considered a very important aspect of the proposal.  The content should address why this proposal should be considered for funding through the Dean’s Transformational Science Award mechanism.  Please do not repeat in the justification statement the information that you have included in the innovation or significance sections of the proposal.  Each section should stand on its own.  Instead, make sure you include information such as how the goals of your grant proposal will contribute to the institutional and departmental missions and make possible the accomplishment of your individual research, as well as larger institutional programmatic goals. Complete as requested on the InfoReady Portal.

NIH Style Biosketch

The biosketch must contain a personal statement relevant to this application that addresses why the proposal is being submitted and why the investigator expects to be successful. This statement should show that the investigator has appropriate experience and training, ongoing record of accomplishments and how these accomplishments have advanced the investigator’s field of study. If this is a multi-investigator project, a biosketch should be submitted for each investigator.  For such collaborative projects the personal statements should include comments on the investigators’ complementary and integrated expertise, any evidence of previous research successes from this collaboration, and programmatic funding envisioned down the road. Must be uploaded as a pdf to the InfoReady Portal.

Specific Aims

Should not exceed one page.  Complete as requested on the InfoReady Portal.

Introduction- for resubmission only

Include a one page introduction explaining how you have addressed the reviewers' comments. Complete as requested on the InfoReady Portal.

Research Strategy - not to exceed four pages

Significance. How does the project address an important problem or a critical barrier to progress in the field?  If the aims of the project are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field and lead to extramural grant funding? Complete as requested on the InfoReady Portal.

Innovation. Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are these novel to one field of research or in a broader sense? Complete as requested on the InfoReady Portal.

Research Design
Present a well-reasoned strategy, a brief methodology section that gives confidence in the proposed approach, how the data will be analyzed, and how the approach will accomplish the specific aims of the project. Include potential problems to achieving the goals of the project and what benchmarks will be used to determine success. The strategy must address feasibility.  The approach must include a discussion of how the limited studies proposed in this intramural application fit into and enhance the bigger picture of the research goals.

Expected Outcomes. Specify expected scientific outcomes and the planned return on investment – how the results that are obtained from the proposed study will enhance the research mission of both the investigator and Jefferson.  This section should include a detailed discussion of the expected return of Jefferson's investment in this proposal, including expected future extramural grant support.

Research Design must be uploaded as a pdf to the InfoReady Portal.


Copy and paste the References from your proposal into the site provided on the InfoReady Portal.

Budget & Budget Justification

Budget: Include a detailed budget of the funds that are requested to accomplish the goals of the proposal. Please note NO salary can be requested for principal investigator (PI).  Download DTSA budget form.  Must be uploaded as a pdf to the InfoReady Portal.

Budget Justification: Include a justification of all personnel and other expenses. Complete as requested on the InfoReady Portal.

Chairperson's Letter of Recommendation

Must be uploaded as a pdf to the InfoReady Portal.