The primary focus of the Eischen lab is on tumor initiation. We want to know how does a normal cell become a cancer cell. Specifically, we want to know what are the genes and pathways that contribute to or inhibit cellular transformation. We study the pathways, proteins, and recently, the miRNA and lncRNA that contribute to or inhibit tumor development with emphasis on the oncogenes Myc and Mdm2. B cell lymphoma is the cancer that we have almost 2 decades of experience studying, and multiple projects utilize this expertise. However, lung, breast, and ovarian carcinomas and cutaneous T cell lymphomas are also studied in the lab. Research in the Eischen lab spans from basic science with and without mouse models through translational research with patient material and bioinformatics.
233 S. 10th Street
Philadelphia, PA 19107