Philadelphia University + Thomas Jefferson University

Bhushan, Alok

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Alok Bhushan, PhD

Contact Dr. Bhushan

901 Walnut Street
9th Floor, Suite 915
Philadelphia, PA 19107

(215) 503-5039
(215) 503-3082 fax

Undergraduate School:

BS (Hons) Chemistry, University of Delhi, India, 1975

Graduate School:

MS Chemistry, University of Delhi, India, 1977
PhD, Punjab Agricultural University, India, 1982

Postgraduate Training:

Johns Hopkins College of Medicine, Baltimore, MD:
Postdoctoral Fellow, 1983-1984;
Medical University of South Carolina, Department of Pediatrics, Charleston, SC:
Postdoctoral Fellow, 1984-1987;
University of Vermont, Department of Pharmacology, Burlington, VT:
Postdoctoral Fellow, 1987-1988

Professional Organizations

American Association of Cancer Research
American Association of College of Pharmacy
American Society of Biochemistry and Molecular Biology
American Association for Advancement of Science
Sigma Xi Scientific Society

Research/Clinical Interests:

Cancer Pharmacology and Signal Transduction focused on Treatment and Prevention



Most Recent Peer-Reviewed Publications

  1. Natural Bioactive Compounds: Alternative Approach to the Treatment of Glioblastoma Multiforme
  2. Toxicity of silicon dioxide nanoparticles in mammalian neural cells
  3. Biochanin A inhibits endothelial cell functions and proangiogenic pathways: Implications in glioma therapy
  4. Co-culturing dorsal root ganglion neurons with schwann cells protects them against the cytotoxic effects of silver nanoparticles
  5. Schwann cells and dorsal root ganglion neurons are differentially susceptible to oxidative stress induced by silicon dioxide nanoparticles
  6. Tyrosine phosphorylation of HSC70 and its interaction with RFC mediates methotrexate resistance in murine L1210 leukemia cells
  7. Biochanin A reduces pancreatic cancer survival and progression
  8. Cytotoxic effects of silver and gold nanoparticles in human glioblastoma U87 cells
  9. Zinc oxide nanoparticles induced apoptosis and necrosis in human neuroblastoma and astrocytoma cells
  10. Interleukin-6 and JAK2/STAT3 signaling mediate the reversion of dexamethasone resistance after dexamethasone withdrawal in 7TD1 multiple myeloma cells
  11. Entry of short multi-wall carbon nanotubes into dorsal root ganglion (DRG) neurons induces cell death
  12. Zinc oxide nanoparticles induce apoptosis and necrosis in hepatocellular carcinoma HepG2 cells
  13. Identification and characterization of a 66-68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells
  14. Cytotoxic effects of short multi-wall carbon nanotubes in dorsal root ganglion (DRG) neurons
  15. Cytotoxic effects of four metallic oxide nanoparticles on dorsal root ganglion (DRG) neurons
  16. Cytotoxicity of magnesium oxide nanoparticles in Schwann cells
  17. Differential cytotoxic effects of titanium oxide nanoparticles on peripheral nervous system neural cells
  18. New in vitro strategy of astrocytoma (astrocytes-like) cells treated with pioglitazone (PPAR gamma agonist) offers neuroprotection against nanoparticles-induced cytotoxicity
  19. Molecular effects of silicon dioxide nanoparticles on cell survival signaling of Dorsal Root Ganglion (DRG) neurons and schwann cells
  20. Effects of silicon dioxide nanoparticles on peripheral nervous system neural cell models