Thomas M. Butler, PhD

Contact Dr. Butler

1020 Locust Street
445 JAH
Philadelphia, PA 19107

(215) 503-6583

Most Recent Peer-reviewed Publications

  1. Remodeling of the rat distal colon in diabetes: Function and ultrastructure
  2. Structural limits on force production and shortening of smooth muscle
  3. A force-activated kinase in a catch smooth muscle
  4. The N-terminal region of twitchin binds thick and thin contractile filaments: Redundant mechanisms of catch force maintenance
  5. Mechanism of catch force: Tethering of thick and thin filaments by twitchin
  6. Myosin cross-bridge kinetics and the mechanism of catch
  7. Catch force links and the low to high force transition of myosin
  8. Twitchin as a regulator of catch contraction in molluscan smooth muscle
  9. Twitchin from molluscan catch muscle. Primary structure and relationship between site-specific phosphorylation and mechanical function
  10. Phosphorylation of molluscan twitchin by the cAMP-dependent protein kinase
  11. The myosin cross-bridge cycle and its control by twitchin phosphorylation in catch muscle
  12. Control of cross-bridge cycling by myosin light chain phosphorylation in mammalian smooth muscle
  13. Phosphorylation of a twitchin-related protein controls catch and calcium sensitivity of force production in invertebrate smooth muscle
  14. Regulation of catch muscle by twitchin phosphorylation: Effects on force, ATPase, and shortening
  15. Phosphorylation of a high molecular weight (-600 kDa) protein regulates catch in invertebrate smooth muscle
  16. Hypertrophy of colonic smooth muscle: Structural remodeling, chemical composition, and force output
  17. Hypertrophy of colonic smooth muscle: Contractile proteins, shortening velocity, and regulation
  18. Thiophosphorylation of the 130-kDa subunit is associated with a decreased activity of myosin light chain phosphatase in α-toxin-permeabilized smooth muscle
  19. Comparison of the effects of 2,3-butanedione monoxime on force production, myosin light chain phosphorylation and chemical energy usage in intact and permeabilized smooth and skeletal muscles
  20. Metabolic characteristics of α-toxin-permeabilized smooth muscle