Renato V. Iozzo, MD, PhD (honoris casusa)

Renato V. Iozzo, MD, PhD (honoris casusa)

Contact Dr. Iozzo

1020 Locust Street
336 JAH
Philadelphia, PA 19107

(215) 503-2208
(215) 923-7969 fax

Most Recent Peer-reviewed Publications

  1. Stepwise impairment of neural stem cell proliferation and neurogenesis concomitant with disruption of blood-brain barrier in recurrent ischemic stroke
  2. Dual regulation of decorin by androgen and Hedgehog signaling during prostate morphogenesis
  3. Extracellular matrix: The driving force of mammalian diseases
  4. Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature
  5. Analysis of progranulin-mediated Akt and MAPK activation
  6. Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling
  7. Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors
  8. The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin
  9. Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium
  10. Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons
  11. The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis
  12. A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia
  13. Steroid hormones are key modulators of tissue mechanical function via regulation of collagen and elastic fibers
  14. Decorin-inducible Peg3 evokes beclin 1-mediated autophagy and thrombospondin 1-mediated angiostasis
  15. Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin
  16. A current view of perlecan in physiology and pathology: A mosaic of functions
  17. The nature and biology of basement membranes
  18. Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy
  19. Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology
  20. Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy