hxc011

Cao Huang, MD

Contact Dr. Huang

1020 Locust Street
506 JAH
Philadelphia, PA 19107

(215) 506-9153

Most Recent Peer-reviewed Publications

  1. Increased Ubqln2 expression causes neuron death in transgenic rats
  2. Identification of TMEM230 mutations in familial Parkinson's disease
  3. Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation
  4. Profiling the genes affected by pathogenic TDP-43 in astrocytes
  5. Pathogenic Ubqln2 gains toxic properties to induce neuron death
  6. Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats
  7. Reactive astrocytes secrete lcn2 to promote neuron death
  8. Pathogenic mutation in VPS35 impairs its protection against MPP+cytotoxicity
  9. XBP1 depletion precedes ubiquitin aggregation and Golgi fragmentation in TDP-43 transgenic rats
  10. Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats
  11. Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats
  12. FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration
  13. Early exposure to paraquat sensitizes dopaminergic neurons to subsequent silencing of PINK1 gene expression in mice
  14. Temporal expression of mutant LRRK2 in adult rats impairs dopamine reuptake
  15. TDP-43 potentiates alpha-synuclein toxicity to dopaminergic neurons in transgenic mice
  16. Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime
  17. Transgenic rat model of neurodegeneration caused by mutation in the TDP gene
  18. Developing tTA transgenic rats for inducible and reversible gene expression
  19. A tightly regulated Pol III promoter for synthesis of miRNA genes in tandem