Yuri Sykulev, MD, PhD

Contact Dr. Sykulev

233 S. 10th Street
Room 706
Philadelphia, PA 19107

(215) 503-4530

Most Recent Peer-reviewed Publications

  1. Extent of MHC clustering regulates selectivity and effectiveness of T cell responses
  2. Assessment of the synaptic interface of primary human t cells from peripheral blood and lymphoid tissue
  3. Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease
  4. Evaluating frequency and quality of pathogen-specific T cells
  5. Integrins influence the size and dynamics of signaling microclusters in a Pyk2-dependent manner
  6. Herman N. Eisen: Mentor to many
  7. Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents
  8. Integrin receptors on tumor cells facilitate NK cell-mediated antibody-dependent cytotoxicity
  9. Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling
  10. The mechanisms of inactivation of the Tag7-Hsp70 cytotoxic complex
  11. Enteric alpha defensins in norm and pathology
  12. Role of the MTOC in T cell effector functions
  13. Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes
  14. Quantum dots as a unique nanoscaffold to mimic membrane receptor clustering
  15. T cell receptor signaling kinetics takes the stage
  16. A novel composite immunotoxin that suppresses rabies virus production by the infected cells
  17. Changing separating distances between immune receptors as a sensitive mechanism regulating T-cell activation
  18. Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain
  19. Can oligomeric T-cell receptor be used as a tool to detect viral peptide epitopes on infected cells?
  20. How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide