Rene Daniel, MD, PhD

Contact Dr. Daniel

1015 Walnut Street
Room 807B
Philadelphia, PA 19107

(215) 503-5725

Most Recent Peer-reviewed Publications

  1. Human vaginal fluid contains exosomes that have an inhibitory effect on an early step of the HIV-1 life cycle
  2. Understanding lentiviral vector chromatin targeting: Working to reduce insertional mutagenic potential for gene therapy
  3. Stem cells and aging: A chicken-or-the-egg issue?
  4. Pyruvate kinase expression (PKM1 and PKM2) in cancer associated fibroblasts drives stromal nutrient production and tumor growth
  5. Proliferating cell nuclear antigen is required for loading of the SMCX/KMD5C histone demethylase onto chromatin
  6. Host Factors that affect Provirus Stability and Silencing
  7. Up-regulation of HIV-1 transduction in nondividing cells by double-strand DNA break-inducing agents
  8. HIV-1 integration site preferences in pluripotent cells
  9. A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors
  10. A role for the Werner syndrome protein in epigenetic inactivation of the pluripotency factor Oct4
  11. Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein
  12. HIV-1 Tat and AIDS-associated cancer: Targeting the cellular anti-cancer barrier?
  13. Integration site selection by retroviral vectors: Molecular mechanism and clinical consequences
  14. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis (Journal of Biological Chemistry (2008) 283, (6572-6583))
  15. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint
  16. Evidence that the Nijmegen breakage syndrome protein, an early sensor of double-strand DNA breaks (DSB), is involved in HIV-1 post-integration repair by recruiting the ataxia telangiectasia-mutated kinase in a process similar to, but distinct from, cellular DSB repair
  17. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis
  18. Pentoxifylline suppresses transduction by HIV-1-based vectors
  19. DNA repair in HIV-1 infection: A case for inhibitors of cellular co-factors?
  20. Following the path of the virus: the exploitation of host DNA repair mechanisms by retroviruses.