tlm004

Timothy L. Manser, PhD

Contact Dr. Manser

233 South Tenth Street
Bluemle Life Sciences Building, Room 302
Philadelphia, PA 19107

(215) 503-4672
(215) 923-7145 fax

Most Recent Peer-reviewed Publications

  1. Humoral Immunity in Mice Transplanted with Hematopoietic Stem Cells Derived from Human Umbilical Cord Blood Recapitulates That of Human Infants
  2. Human B-1 and B-2 B cells develop from Lin-CD34+CD38lostem cells
  3. YY1 is required for germinal center B cell development
  4. Establishment and Characterization of Orthotopic Mouse Models for Human Uveal Melanoma Hepatic Colonization
  5. Evaluation of the efficiency of human immune system reconstitution in NSG mice and NSG mice containing a human HLA.A2 transgene using hematopoietic stem cells purified from different sources
  6. Cutting edge: Macrophages are required for localization of antigen-activated b cells to the follicular perimeter and the subsequent germinal center response
  7. A germline-competent embryonic stem cell line from NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (NSG) mice
  8. Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing
  9. Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever
  10. Immunologic research at Thomas Jefferson University: A recent history
  11. Human immune system mice: Current potential and limitations for translational research on human antibody responses
  12. Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments
  13. Expression of cellular FLIP by B cells is required for their participation in an immune response
  14. Germinal center reutilization by newly activated B cells
  15. The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints
  16. Initial Clonal Expansion of Germinal Center B Cells Takes Place at the Perimeter of Follicles
  17. Influence of B cell antigen receptor expression level on pathways of B cell tolerance induction
  18. A role for cFLIP in B cell proliferation and stress MAPK regulation
  19. Specialization and Complementation of Humoral Immune Responses to Infection: Preface
  20. Influence of fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen