dch101

Douglas C. Hooper, PhD

Contact Dr. Hooper

1020 Locust Street
JAH 452
Philadelphia, PA 19107

(215) 503-1774
(215) 923-7745 fax

Most Recent Peer-reviewed Publications

  1. Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis
  2. Type 1 immune mechanisms driven by the response to infection with attenuated rabies virus result in changes in the immune bias of the tumor microenvironment and necrosis of mouse GL261 brain tumors
  3. Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells
  4. Human parechovirus and enterovirus initiate distinct CNS innate immune responses: Pathogenic and diagnostic implications
  5. Immune biomarkers of treatment failure for a patient on a phase i clinical trial of pembrolizumab plus radiotherapy
  6. Serum exosomes and cytokines promote a T-helper cell type 2 environment in the peripheral blood of glioblastoma patients
  7. T-bet is required for the rapid clearance of attenuated rabies virus from central nervous system tissue
  8. Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation
  9. Enhancement of glioma-specific immunity in mice by “NOBEL”, an insulin-like growth factor 1 receptor antisense oligodeoxynucleotide
  10. Glioblastoma exosomes and IGF-1R/AS-ODN are immunogenic stimuli in a translational research immunotherapy paradigm
  11. Pre- and post-exposure safety and efficacy of attenuated rabies virus vaccines are enhanced by their expression of IFNγ
  12. Expression of interferon gamma by a recombinant rabies virus strongly attenuates the pathogenicity of the virus via induction of type I interferon
  13. Differential host immune responses after infection with wild-type or lab-attenuated rabies viruses in dogs
  14. Use of advanced magnetic resonance imaging techniques in neuromyelitis optica spectrum disorder
  15. Limited brain metabolism changes differentiate between the progression and clearance of rabies virus
  16. Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers
  17. Intramuscular inoculation of mice with the live-attenuated recombinant rabies virus TriGAS results in a transient infection of the draining lymph nodes and a robust, long-lasting protective immune response against rabies
  18. Presence of Virus Neutralizing Antibodies in Cerebral Spinal Fluid Correlates with Non-Lethal Rabies in Dogs
  19. Aleuria Aurantia Lectin (AAL)-Reactive Immunoglobulin G Rapidly Appears in Sera of Animals following Antigen Exposure
  20. Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei