sbm001

Steven B. McMahon, PhD

Contact Dr. McMahon

233 South 10th Street
BLSB 609
Philadelphia, PA 19107

(215) 503-9064

Most Recent Peer-reviewed Publications

  1. Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation
  2. Repression of telomerase gene promoter requires human-specific genomic context and is mediated by multiple HDAC1-containing corepressor complexes
  3. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction
  4. Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres
  5. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
  6. The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness
  7. Retraction Notice to: Nuclear receptor function requires a TFTC-type histone acetyl transferase complex
  8. MYC and the control of apoptosis
  9. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
  10. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)
  11. P53: The TRiC Is Knowing When to Fold 'Em
  12. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer
  13. Dachshund binds p53 to block the growth of lung adenocarcinoma cells
  14. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex
  15. Dynamic regulation of mitochondrial transcription as a mechanism of cellular adaptation
  16. MYST protein acetyltransferase activity requires active site lysine autoacetylation
  17. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC
  18. Enzymatic assays for assessing histone deubiquitylation activity
  19. Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53
  20. The Role of Epigenetic Modifications in Cancer