Philadelphia University + Thomas Jefferson University

Strayer, David S.

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David S. Strayer, MD, PhD

Contact Dr. Strayer

1020 Locust Street
Jefferson Alumni Hall, Suite 251
Philadelphia, PA 19107

(215) 503-1087
(215) 503-1156 fax

Medical School

MD, University of Chicago - 1976
PhD, University of Chicago - 1976

University Appointment

Professor

Research and Clinical Interests

Aids; Bioterrorism; Botulinum Toxin; Cell Biology; Cell Growth Regulation; Complementary DNA; DNA Footprinting; Gene Expression; Gene Induction Repression; Gene Therapy; Genetic Promoter Element; Genetics; Molecular Cloning; Nucleic Acid Sequence; Poxviruses; Site Directed Mutagenesis; Sv40; Tissue Cell Culture; Transcription Factor; Transfection; Tumor Suppressor Gene; Viral Genetics; Virology

Publications

Most Recent Peer-Reviewed Publications

  1. Histopathologic identification of Trypanosoma cruzi (Chagas') encephalitis in an AIDS patient
  2. Assessment of apoptosis and neuronal loss in animal models of HIV-1-associated neurocognitive disorders
  3. Erratum to: Interaction of Paroxetine with Mitochondrial Proteins Mediates Neuroprotection (Neurotherapeutics, (2015), 12, (200-216), DOI 10.1007/s13311-014-0315-9)
  4. Migration and differentiation of bone marrow progenitor cells in the adult brain
  5. Generation of recombinant SV40 vectors for gene transfer
  6. Interaction of Paroxetine with Mitochondrial Proteins Mediates Neuroprotection
  7. Expression of GluR6, a kainate receptor, in human lymphocytes
  8. Ethanol stimulates angiogenesis via vascular endothelial growth factor and protects from ischemia and reperfusion injury
  9. Relationship between the chemokine receptor CCR5 and microglia in neurological disorders: Consequences of targeting CCR5 on neuroinflammation, neuronal death and regeneration in a model of epilepsy
  10. Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
  11. HIV-1-associated neurocognitive disorder: Role of oxidative stress and protection by gene delivery of antioxidant enzymes
  12. HIV -1 GP120 induces blood -brain barrier abnormalities: Pathophysiology and therapeutic consequences
  13. Modulation of microglial reaction in brain injury by novel therapeutic tools based on gene therapy approaches
  14. Ethanol protects from injury due to ischemia and reperfusion by increasing vascularity via vascular endothelial growth factor
  15. Gene delivery of antioxidant enzymes inhibits human immunodeficiency virus type 1 gp120-induced expression of caspases
  16. Blood-brain barrier abnormalities caused by HIV-1 gp120: Mechanistic and therapeutic implications
  17. HIV-1 Tat neurotoxicity: A model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes
  18. Raphael Rubin, 1956-2011.
  19. Intracisternal rSV40 administration provides effective pan-CNS transgene expression
  20. HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy