Philadelphia University + Thomas Jefferson University

Strayer, David S.

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David S. Strayer, MD, PhD

Contact Dr. Strayer

1020 Locust Street
Jefferson Alumni Hall, Suite 251
Philadelphia, PA 19107

(215) 503-1087
(215) 503-1156 fax

Medical School

MD, University of Chicago - 1976
PhD, University of Chicago - 1976

University Appointment


Research and Clinical Interests

Aids; Bioterrorism; Botulinum Toxin; Cell Biology; Cell Growth Regulation; Complementary DNA; DNA Footprinting; Gene Expression; Gene Induction Repression; Gene Therapy; Genetic Promoter Element; Genetics; Molecular Cloning; Nucleic Acid Sequence; Poxviruses; Site Directed Mutagenesis; Sv40; Tissue Cell Culture; Transcription Factor; Transfection; Tumor Suppressor Gene; Viral Genetics; Virology


Most Recent Peer-Reviewed Publications

  1. Gene Delivery of Antioxidant Enzymes in HIV-1-Associated Neurocognitive Disorder
  2. Histopathologic identification of Trypanosoma cruzi (Chagas') encephalitis in an AIDS patient
  3. Assessment of apoptosis and neuronal loss in animal models of HIV-1-associated neurocognitive disorders
  4. Erratum to: Interaction of Paroxetine with Mitochondrial Proteins Mediates Neuroprotection (Neurotherapeutics, (2015), 12, (200-216), DOI 10.1007/s13311-014-0315-9)
  5. Migration and differentiation of bone marrow progenitor cells in the adult brain
  6. Generation of recombinant SV40 vectors for gene transfer
  7. Interaction of Paroxetine with Mitochondrial Proteins Mediates Neuroprotection
  8. Role of oxidative stress in HIV-1-associated neurocognitive disorder and protection by gene delivery of antioxidant enzymes
  9. Oxidative stress is associated with neuroinflammation in animal models of HIV-1 tat neurotoxicity
  10. Expression of GluR6, a kainate receptor, in human lymphocytes
  11. Ethanol stimulates angiogenesis via vascular endothelial growth factor and protects from ischemia and reperfusion injury
  12. Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
  13. Relationship between the chemokine receptor CCR5 and microglia in neurological disorders: Consequences of targeting CCR5 on neuroinflammation, neuronal death and regeneration in a model of epilepsy
  14. HIV-1-associated neurocognitive disorder: Role of oxidative stress and protection by gene delivery of antioxidant enzymes
  15. Modulation of microglial reaction in brain injury by novel therapeutic tools based on gene therapy approaches
  16. HIV -1 GP120 induces blood -brain barrier abnormalities: Pathophysiology and therapeutic consequences
  17. Ethanol protects from injury due to ischemia and reperfusion by increasing vascularity via vascular endothelial growth factor
  18. Gene delivery of antioxidant enzymes inhibits human immunodeficiency virus type 1 gp120-induced expression of caspases
  19. Blood-brain barrier abnormalities caused by HIV-1 gp120: Mechanistic and therapeutic implications
  20. HIV-1 Tat neurotoxicity: A model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes