Philadelphia University + Thomas Jefferson University

Harrop, James S

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James S. Harrop, MD, FACS

Contact Dr. Harrop

900 Walnut Street
Philadelphia, PA 19107

(215) 955-7000

Research and Clinical Interests

Spinal cord Injury, Spinal Tumors, Degenerative spine conditions

My research focuses on... Improving the neurologic status of patients after spinal cord injuries. Several years ago there was the belief that patients with spinal cord injuries had no potential to improve neurologically. Over the last several decades through a better understanding of the pathophysiology of spinal cord injury and the nervous system patients outcomes have improved. Presently through early decompression and reconstruction of a patient's spinal column, we are seeing continued and progressively better neurologic recoveries. However, we still have a long way further to improve. The uses of translational strategies such as anti-apoptotic agents are showing future promise. These advances are aimed for not only individuals affected with trauma induced spinal conditions, but also for the treatment of spinal tumors and degenerative conditions.

The techniques that I use in my research are translation research with scientists utilizing molecular and stem cell therapy to aid in the repair of spinal cord injuries. In addition to clinical research techniques with prospective and retrospective studies.

I hope that my findings will be used to improve the quality of lives for individuals affected with spine and spinal cord disorders.

Publications

Most Recent Peer-Reviewed Publications

  1. Thoracic spinal osteochondroma: A rare presentation of spinal cord compression
  2. Intraosseous hemangioblastoma of the cervical spine: Case report
  3. A Clinical Practice Guideline for the Management of Acute Spinal Cord Injury: Introduction, Rationale, and Scope
  4. Efficacy and Safety of Methylprednisolone Sodium Succinate in Acute Spinal Cord Injury: A Systematic Review
  5. Timing of Decompression in Patients With Acute Spinal Cord Injury: A Systematic Review
  6. Efficacy, Safety, and Timing of Anticoagulant Thromboprophylaxis for the Prevention of Venous Thromboembolism in Patients With Acute Spinal Cord Injury: A Systematic Review
  7. A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Rehabilitation
  8. A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Role of Baseline Magnetic Resonance Imaging in Clinical Decision Making and Outcome Prediction
  9. A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
  10. A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Use of Methylprednisolone Sodium Succinate
  11. A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury and Central Cord Syndrome: Recommendations on the Timing (≤24 Hours Versus >24 Hours) of Decompressive Surgery
  12. A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Anticoagulant Thromboprophylaxis
  13. Resource utilization for non-operative cervical radiculopathy: Management by surgeons versus non-surgeons
  14. Cervical Spondylodiscitis: Presentation, Timing, and Surgical Management in 59 Patients
  15. Surgery for metastatic spine tumors in the elderly. Advanced age is not a contraindication to surgery!
  16. Anterior cervical infection: Presentation and incidence of an uncommon postoperative complication
  17. Update on upper cervical spine injury classifications
  18. Non-pharmacologic interventions for SCI patients: Hypertension and hypothermia
  19. Response
  20. Thoracolumbar Trauma Classification