Philadelphia University + Thomas Jefferson University

Curtis, Mark T.

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Mark T. Curtis, MD, PhD

Contact Dr. Curtis

132 South 10th Street
Main Building, Suite 263
Philadelphia, PA 19107

(215) 955-6206

Medical School

MD, Thomas Jefferson University - 1982

University Appointment

Associate Professor

Other Professional Appointments

Director of Neuropathology

Assistant Director of Autopsy Pathology

Director, Pathology Laser Microdissection Facility

Program Director, Pathology Residency

Research and Clinical Interests

Viral Diseases of the Central Nervous System

Demyelinating Disorders of the Central Nervous System


Most Recent Peer-Reviewed Publications

  1. LINGO-1-Fc-Transduced Neural Stem Cells Are Effective Therapy for Chronic Stage Experimental Autoimmune Encephalomyelitis
  2. Teratoma of the spinal cord in an adult: Report of a rare case and review of the literature
  3. Lumbar paraganglioma
  4. Neural Stem Cells Engineered to Express Three Therapeutic Factors Mediate Recovery from Chronic Stage CNS Autoimmunity
  5. Intravenous injection of AAVrh10-GALC after the neonatal period in twitcher mice results in significant expression in the central and peripheral nervous systems and improvement of clinical features
  6. Succinate dehydrogenase-deficient gastrointestinal stromal tumor: A clinical example and discussion of the entity
  7. Two cases of spinal, extraosseous, intradural ewing's sarcoma/peripheral neuroectodermal tumor: Radiologic, pathologic, and molecular analysis
  8. Homonymous hemianopia due to Erdheim-Chester disease
  9. Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers
  10. STAT5A/B gene locus undergoes amplification during human prostate cancer progression
  11. Extended normal life after AAVrh10-mediated gene therapy in the mouse model of krabbe disease
  12. Accelerated and enhanced effect of CCR5-transduced bone marrow neural stem cells on autoimmune encephalomyelitis
  13. CNS recruitment of CD8+ T lymphocytes specific for a peripheral virus infection triggers neuropathogenesis during polymicrobial challenge
  14. Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis
  15. Lymphocytic choriomeningitis virus-induced mortality in mice is triggered by edema and brain herniation
  16. Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis
  17. Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy
  18. Revisiting anaplastic astrocytomas I: An expansive growth pattern is associated with a better prognosis
  19. Complex choristoma of the gyrus rectus: A distinct clinicopathologic entity?
  20. Biochemical and pathological evaluation of long-lived mice with globoid cell leukodystrophy after bone marrow transplantation