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Cancer cell Biology and Signaling Program


PROGRAM OVERVIEW



Andrew E. Aplin, Ph.D., Program Leader
George C. Prendergast, Ph.D., Program Co-Leader



J. Keen, Ph.D.: clathrin binding site

The mission of the Cancer Cell Biology and Signaling (CCBS) Program is to elucidate the role of cell signaling in regulating cell growth, differentiation, apoptosis and migration, and to assist Cancer Center members in their efforts to harness this understanding into approaches to cancer detection, prognosis and treatment. Program members focus on three major areas of research: 1) understanding the molecular mechanisms involved in the regulation of cell growth and differentiation with an emphasis on the role of tyrosine kinase and G protein-coupled receptor signaling pathways; 2) elucidating the molecular mechanisms regulating cell apoptosis; and 3) addressing the role of the extracellular matrix in regulating cell growth and migration.



The Program is led by Drs. Andrew Aplin and George Prendergast, both of whom have extensive administrative experience and established research programs focused on cell signaling and cancer. The Program is comprised of members from nine departments and three Institutions (Jefferson, Lankenau Institute for Medical Research and Drexel). Program members have authored a total of 650 publications during the last 5 years.



Cancer Cell Biology and Signaling Program



Emad S. Alnemri, Ph.D.

Professor, Biochemistry & Molecular Biology

Program Member

Dr. Alnemri's PubMed

David Andrews, M.D.

Associate Professor, Neurosurgery

Program Member

Dr. Andrews's PubMed

Andrew E. Aplin, Ph.D.

Professor, Cancer Biology

Program Leader

Dr. Aplin's PubMed

Roger Armen, Ph.D.

Assistant Professor, Medicinal Chemistry - Pharmacy

Program Member

Dr. Armen's PubMed

Jane Azizkhan-Clifford, Ph.D.

Professor, Biochemistry and Molecular Biology, Drexel University College of Medicine

Program Member

Dr. Azizkhan-Clifford's PubMed

Jeffrey Benovic, Ph.D.

Professor, Biochemistry & Molecular Biology

Program Member

Dr. Benovic's PubMed

Paul Campbell, Ph.D.

Assistant Professor, Pharmacology & Physiology, Drexel College of Medicine

Associate Member

Dr. Campbell's PubMed

Jaime Caro, M.D.

Professor, Hematology

Program Member

Dr. Caro's PubMed

Mon-Li Chu, Ph.D.

Professor, Dermatology & Cutaneous Biology

Program Member

Dr. Chu's PubMed

Gino Cingolani, Ph.D.

Associate Professor, Biochemistry & Molecular Biology

Program Member

Dr. Cingolani's PubMed

Masumi Eto, Ph.D.

Associate Professor, Molecular Physiology & Biophysics

Program Member

Dr. Eto's PubMed

Mark Fortini, Ph.D.

Associate Professor, Biochemistry & Molecular Biology

Program Member

Dr. Fortini's PubMed

Gyorgy Hajnoczky, M.D.

Professor, Pathology, Anatomy and Cell Biology

Program Member

Dr. Hajnoczky's PubMed

Renato V. Iozzo, M.D.

Professor, Pathology, Anatomy & Cell Biology

Program Member

Dr. Iozzo's PubMed

Pooja Jain, Ph.D.

Associate Professor, Microbiology/Immunology, Drexel College of Medicine

Program Member

Dr. Jain's PubMed

Sergio A. Jimenez, M.D.

Professor, Dermatology & Cutaneous Biology

Program Member

Dr. Jimenez's PubMed

James H. Keen, Ph.D.

Professor, Biochemistry & Molecular Biology

Program Member

Dr. Keen's PubMed

My G. Mahoney, Ph.D.

Associate Professor, Dermatology and Cutaneous Biology

Program Member

Dr. Mahoney's PubMed

Olympia Meucci, M.D., Ph.D.

Professor, Pharmacology and Physiology, Drexel College of Medicine

Program Member

Dr. Meucci's PubMed

Stephen Peiper, M.D.

Professor, Pathology, Anatomy & Cell Biology

Program Member

Dr. Peiper's PubMed

Raymond Penn, Ph.D.

Medicine

Program Member

Dr. Penn's PubMed

Richard G. Pestell, M.D., Ph.D.

Professor, Cancer Biology

Program Member

Dr. Pestell's PubMed

George C. Prendergast, Ph.D.

Lankenau Institute for Medical Research

Program Co-Leader

Dr. Prendergast's PubMed

Mauricio Reginato, Ph.D.

Associate Professor, Biochemistry and Molecular Biology, Drexel College of Medicine

Program Member

Dr. Reginato's PubMed

Natalia Riobo, Ph.D.

Assistant Professor, Biochemistry and Molecular Biology

Program Member

Dr. Riobo's PubMed

Ulrich Rodeck, M.D.

Professor, Dermatology & Cutaneous Biology

Program Member

Dr. Rodeck's PubMed

Nianli Sang, Ph.D.

Associate Professor, Biology, Drexel University

Program Member

Dr. Sang's PubMed

Takami Sato, M.D., Ph.D.

Associate Professor, Medical Oncology

Program Member

Dr. Sato's PubMed

Charles P. Scott, Ph.D.

Assistant Professor, Biochemistry & Molecular Biology

Program Member

Dr. Scott's PubMed

Philip Wedegaertner, Ph.D.

Associate Professor, Biochemistry & Molecular Biology

Program Member

Dr. Wedegaertner's PubMed

Maria Werner-Wasik, M.D.

Assistant Professor, Radiation Oncology

Program Member

Dr. Werner-Wasik's PubMed

Margaret Wheatley, Ph.D.

Professor, Biomedical Engineering, Drexel University

Program Member

Dr. Wheatley's PubMed

Brian Wigdahl, Ph.D.

Professor, Biochemistry and Molecular Biology, DrexelCollege of Medicine

Program Member

Dr. Wigdahl's PubMed

Edward Winter, Ph.D.

Associate Professor, Biochemistry & Molecular Biology

Program Member

Dr. Winter's PubMed

The program members' publications in 2011 and 2012




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