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Endocrine Mechanisms and Hormone Action in Cancer Program
PROGRAM OVERVIEW
Hallgeir Rui, M.D., Ph.D., Program Leader
Leonard Gomella, M.D., Program Co-Leader
 The overarching goal of the Endocrine Mechanisms and Hormone Action in Cancer Program is to discover molecular alterations and signatures of cancer of hormone regulated tissues, and to translate these findings into new strategies for effective detection, diagnosis, and cure. A main focus of this new Program is on hormone responsive and hormone refractory breast and prostate cancer, but studies of other endocrine-related malignancies are also included in the Program. Aligned with the NIH Roadmap, the program maintains a strong commitment to and emphasis on translational research, with ongoing interactions with clinical Departments of Pathology, Surgery, Radiation Oncology, and Medical Oncology. A Program grant application on Breast Cancer Differentiation has already been submitted from this Program.
Scientific Goals
- Exploiting mechanisms of hormone action for improved therapy and prevention of hormone responsive and hormone refractory cancer
- Developing innovative strategies and technologies for detection, diagnosis, and monitoring of hormone responsive and hormone refractory cancer
- Designing pre-clinical models for drug response prediction to facilitate improved tailored treatment of hormone responsive and hormone refractory cancer
Endocrine Mechanisms and Hormone Action in Cancer Program Faculty
Bonita Falkner, Ph.D. |
Professor, Nephrology |
Program Member |
Dr. Falkner's PubMed |
Leonard P. Freedman, Ph.D. |
Professor, Jefferson Medical College |
Program Member |
Dr. Freedman's PubMed |
Leonard G. Gomella, M.D. |
Professor, Urology |
Program Co-Leader |
Dr. Gomella's PubMed |
Wm. Kevin Kelly, D.O. |
Professor, Medical Oncology |
Program Member |
Dr. Kelly's PubMed |
Karen E. Knudsen, Ph.D. |
Professor, Cancer Biology |
Program Member |
Dr. Knudsen's PubMed |
Sigrid Langhan, Ph.D. |
Assistant Professor, Pediatrics |
Program Member |
Dr. Langhan's PubMed |
Lucia Languino, Ph.D. |
Professor, Cancer Biology |
Program Member |
Dr. Languino's PubMed |
Michael Lisanti, M.D., Ph.D. |
Professor, Stem Cell Biology and Regenerative Medicine |
Program Member |
Dr. Lisanti's PubMed |
Diane M Merry, Ph.D. |
Associate Professor, Bichemistry & Molecular Pharmacology |
Program Member |
Dr. Merry's PubMed |
Daniel Monti, M.D. |
Associate Professor, Center for Integrative Medicine |
Program Member |
Dr. Monti's PubMed |
Andrea Morrione, Ph.D. |
Research Associate Professor, Urology |
Program Member |
Dr. Morrione's PubMed |
Marja Nevalainen, M.D., Ph.D. |
Associate Professor, Cancer Biology, Medical Oncology, and Urology |
Program Member |
Dr. Nevalainen's PubMed |
Richard G. Pestell, M.D., Ph.D. |
Professor, Cancer Biology |
Program Member |
Dr. Pestell's PubMed |
Andrew Quong, Ph.D. |
Associate Professor, Cancer Biology |
Program Member |
Dr. Quong's PubMed |
Ayyappan Rajasekaran, Ph.D. |
Professor, Pediatrics |
Program Member |
Dr. Rajasekaran's PubMed |
Hallgeir Rui, M.D., Ph.D. |
Professor, Cancer Biology |
Program Leader |
Dr. Rui's PubMed |
Takemi Tanaka, Ph.D. |
Assistant Professor, Pharmaceutical Sciences, JSP |
Program Member |
Dr. Tanaka's PubMed |
Madhukar (Mathew) L. Thakur, Ph.D. |
Professor, Radiology |
Program Member |
Dr. Thakur's PubMed |
Edouard Trabulsi, M.D. |
Assistant Professor, Urology |
Program Member |
Dr. Trabulsi's PubMed |
Janice Walker, Ph.D. |
Research Assistant Professor, Pathology, Anatomy & Cell Biology |
Program Member |
Dr. Walker's PubMed |
Eric Wickstrom, Ph.D. |
Professor, Biochemistry & Molecular Cell Biology |
Program Member |
Dr. Wickstrom's PubMed |
Agnieszka Witkiewicz, M.D. |
Assistant Professor, Pathology, Anatomy & Cell Biology |
Program Member |
Dr. Witkiewicz's PubMed |
Kongming Wu, Ph.D. |
Assistant Professor, Cancer Biology |
Program Member |
Dr. Wu's PubMed |
The program members' publications in 2005 and 2006
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