Recently Approved KCC Clinical Trials

08R.69 :    Brain & Central Nervous System

Title:  Surgical versus Nonoperative Treatment of Metastatic Epidural Spinal Cord Compression (MESCC). Quality of Life and Cost-Effectiveness Outcomes. (5-prospective data collection; 7-interviews; questionnaires)

08F.126 :    Breast

Purpose:  To determine the disease-free survival of patients (defined as invasive disease-free survival (IFDS) with lymph node positive and high risk lymph node negative breast cancer randomized to treatment with either doxorubicin/cyclophosphamide plus placebo followed by paclitaxel (AC + Placebo > T + Placebo) or the same chemotherapy regimen plus bevacizumab.

Title:  A Double Blind Phase III Trial of Doxorubicin and Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer

08G.89 :    Colorectal

Purpose:  In order of priority, to determine (1) tailored navigation intervention (TNI) impact on colorectal cancer [CRC] screening utilization, (2) TNI impact on CRC screening preference, and (3) TNI impact on perceptions about CRC screening.

Title:  Increasing Colon Cancer Screening in Primary Care Among African Americans

08F.112 :    Ovary

Purpose:  To assess the ability of the YKL-40 serum marker to detect response or lack of response to primary chemotherapy in FIGO stage III or IV invasive epithelial ovarian, primary peritoneal, or fallopian tube cancer. To compare the predictive accuracy of YKL-40 with CA125.

Title:  GOG #0235: A Prospective, Longitudinal Study of YKL-40 in Patients with FIGO Stage III or IV Invasive Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Undergoing Primary Chemotherapy