Recently Approved KCC Clinical Trials

09f.470 :    Brain & Central Nervous System

Purpose:  1. To assess whether concurrent radiotherapy with daily temozolomide chemotherapy improves overall survival as compared to no daily temozolomide in non-1p/19q deleted anaplastic glioma. 2. To assess whether adjuvant temozolomide chemotherapy improves survival as compared to no adjuvant temozolomide chemotherapy in non-1p/19q deleted anaplastic glioma

Title:  RTOG 0834/EORTC 26053_22054/NCIC CTG CEC.1 PHASE III TRIAL ON CONCURRENT AND ADJUVANT TEMOZOLOMIDE CHEMOTHERAPY IN NON-1P/19Q DELETED ANAPLASTIC GLIOMA: THE CATNON INTERGROUP TRIAL

09F.469 :    Lung & other Thoracic Malignancies

Purpose:  Primary Objectives:To evaluate the progression-free survival of patients with extensive stage small cell lungcancer (SCLC-ED) treated with cisplatin and etoposide (CE), CE with hedgehog (HH)inhibitor GDC-0449, and CE with Insulin-like Growth Factor-I Receptor (IGF-1R) Monoclonal Antibody (IMC-A12).

Title:  E1508: A Randomized Phase II Study of Cisplatin and Etoposide In Combination with Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients with Extensive Stage Small Cell Lung Cancer