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Side Effects of a Permanent Implant

Frequently Asked Questions about Permanent Radioactive Seed Implants for Prostate Cancer

 

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Main FAQ Page

Prostate Cancer Issues

Logistics of a Permanent Implant

Side Effects of a Permanent Implant

Potency after a Permanent Implant

Radiation Safety after Permanent Implant

Pros and Cons of Implants

Follow-up after a Permanent Implant


Urinary Side effects after a Permanent Implant

 

What can the patient expect to feel like after the procedure?

Like all procedures, the response can vary. The procedure causes minimal trauma to the region beneath the scrotum, but there can be some tenderness and bruising. Patients require no medications for pain. Patients are not limited in their activities after the procedure.

 

What side effects might occur days after the procedure and for how long a period of time they continue?

As a result of the implant procedure, some men experience mild discomfort in the groin area for two to three days. Some blood may be seen in the urine and sperm for a few days after the procedure similiar to what was experienced after the prostate biopsy. This is normal and stops after two to three days. The scrotal and perineal area can also become swollen/bruised or black and blue. The effects of the radiation from the seeds usually begin one to two weeks after seed implantation. The main symptoms are urinary difficulties such as frequency, urgency, weak stream or slight pain. These can last for 2-6 months. These can usually be effectively managed with simple medications.

 

What is the likelihood of blood in the urine and passing blood clots after the procedure?

This is common during the first couple of days and resolves without requiring intervention. Occasionally it lasts longer or occurs spontaneously some time after the implant. If you should have any questions or concerns contact your physician.

 

Can seed implantation cause long or short-term incontinence?

The risk of long-term incontinence after either seed implant alone or in combination with external beam radiation in the typical, (non-TURP), patient is extremely rare, less than 1%. Over the short term, some patients experience significant urgency and may have difficulty reaching the restroom without some slight dribbling. This resolves over one to two months.

 

If the patient had BPH (benign prostatic hypertrophy) prior to seeding, will it go away or return later?

A good question that we don't know the answer to.

 

What effect would a TURP, (transurethral revection of prostate) either previous to or after seed implantation have on treatment?

In patients with a large TURP defect, it is technically challenging to perform a good implant. In our experience TURP patients who received an implant at Thomas Jefferson University have not experienced an increased risk of urinary incontinence. TURP after the implant also imparts a risk of incontinence. Therefore, we try to avoid doing a TURP in implant patients. When a TURP is necessary after implant, someone who understands the problems associated with it should perform the procedure.

 

Please explain why nighttime is worse than the daytime for urine retention and difficulties in urination?

For many men nighttime urination is a different experience than the daytime, with often a slower stream or difficulty initiating a stream. The reason(s) for this are unclear. There seems to be more urine made at night than during the day. Alpha-blockers (Cardura, Flomax or Hytrin) are often prescribed to help minimize this symptom. Generally this worsening of the urinary stream at night goes away over a few months.

 

Do you recommend any strategies for alleviating nighttime urinary problems?

Alpha-blockers can often help a lot. Other techniques to help flow are: walking around, getting into a warm shower or bathtub and using anti-inflammatory medications.

 

What are the chances the patient will be affected by prostatitis after seeding?

Prostate brachytherapy delivers a high dose of radiation to the prostate and periprostatic tissue. The major treatment related symptoms are urinary, due to radiation prostatitis. Nearly all patients develop some degree of dysuria, daytime urinary frequency and increased nocturia which typically resolves as the seeds lose their energy, over a period of months.

 

Is there any chance of infection?

Yes, however, rare. We use intravenous antibiotics in the operating room. None are or given when you leave the hospital. There have been no urinary infections in our patients who have received an implant.

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